(Last Updated On: June 22, 2023)

Does Benadryl Help with Asthma?

Uses and Precautions

Asthma is characterized by inflammation and narrowing of the airways in the lungs. In some cases, doctors may prescribe Benadryl or another antihistamine to relieve mild asthma symptoms. However, it should never be used as a replacement for an inhaler or prescribed asthma medications.

You boy with asthma using inhaler

Benefits of Using Antihistamines for Asthma

Histamines are chemicals released by the body in response to allergen exposure, causing inflammation and narrowing of the airways in asthma patients. This can lead to difficulty breathing, wheezing, and coughing. Antihistamines like Benadryl work by blocking histamine receptors, reducing inflammation, and improving airway function.

In addition to their direct effect on histamine receptors, some studies suggest that antihistamines may have indirect benefits for asthma patients. For example, a study published in The Journal of Asthma found that children with persistent asthma who were treated with an oral antihistamine had fewer flare-ups compared to those who did not receive the treatment.

Risks of Using Antihistamines for Asthma

One of the main concerns with using antihistamines for asthma is their potential side effects, including drowsiness, dry mouth, blurred vision, constipation, diarrhea, and dizziness. Taking high doses of antihistamines can also cause heart palpitations and other cardiac side effects.

In some cases antihistamines may worsen asthma symptoms by causing airway constriction. This is because they can have a drying effect on mucus membranes, including those lining the airways, which can make it difficult to breathe.

Certain types of antihistamines may interact with other medications commonly used to treat asthma, potentially leading to harmful side effects or reduced effectiveness. Some antihistamines may also interact with antidepressants or blood pressure medications. In addition, using Benadryl for asthma may mask underlying issues that require medical attention, which can lead to more severe complications down the line.

Developing an Effective Treatment Plan for Asthma

While antihistamines may have a role to play in managing certain types of asthma symptoms, they should not be used as the sole treatment. Work with your healthcare provider to develop a comprehensive treatment plan that takes into account your unique needs and circumstances. This may include a combination of medications such as bronchodilators, corticosteroids, or immunomodulators, as well as lifestyle modifications such as avoiding triggers and monitoring symptoms.

Before adding any new medication or supplement to your asthma treatment plan, make sure you speak with a healthcare provider. They will be able to assess your medical history and current symptoms to determine if antihistamines are appropriate for you, as well as recommend specific types of antihistamines based on your individual needs.


Used in conjunction with other medications and lifestyle modifications, antihistamines like Benadryl can be a useful tool in managing asthma symptoms. While they are not a primary treatment for asthma, they can help alleviate symptoms caused by allergies that may trigger asthma attacks. Consult with a doctor before using antihistamines for asthma treatment to properly incorporate them into a comprehensive treatment plan.

Top Pick

Alen BreatheSmart 45i
Air Purifier
$430 Buy Now

Best Air Purifiers for Asthma

Alen Breathesmart 45i $429 Buy Now
Austin Air
Healthmate Plus
Air Purifier

$855 Buy Now
Air Purifier

$900 Buy Now
Classic 605
Air Purifier

$495 Buy Now
AirMega 400
Air Purifier

$450 Buy Now